Loratadine

What is loratadine?

Loratadine is a non-drowsy antihistamine used to relieve allergy symptoms such as sneezing, itching, and runny nose. It’s available under brand names like Clarityn and can be purchased in shops and pharmacies without a prescription in the UK (but can also be prescribed by a doctor). Loratadine is commonly taken during allergy season but can also be used year-round for persistent allergies[1]. 

What is loratadine used to treat?

Loratadine is effective at relieving symptoms caused by allergic reactions. It is commonly used to treat[1]: 

• Hay fever (seasonal allergic rhinitis) 

• Perennial allergic rhinitis (year-round allergies to things like dust mites or pets) 

• Urticaria (hives) 

• Insect bite or sting reactions 

• Skin allergies such as eczema or contact dermatitis  

How does loratadine work?

Loratadine works by blocking the action of histamine, a substance your body releases during an allergic reaction. Histamine is responsible for symptoms like itching, swelling, sneezing, and watery eyes. By blocking histamine receptors, loratadine reduces these effects without causing significant drowsiness in most people[1]. 

Who can take loratadine?

Loratadine is generally suitable for[1]: 

• Adults 

• Children aged 2 years and older, depending on the formulation 

You should speak to a doctor if you: 

• Have severe liver problems 

• Are pregnant or trying to get pregnant 

• Are allergic to food additives 

• Have epilepsy or other conditions that have a risk of seizures 

• Have severe liver failure 

• Are allergic to loratadine or its ingredients 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

What is the typical dosage of loratadine?

Loratadine comes in 10mg tablets and as a liquid medicine (labelled either 5mg/5ml or 1mg/1ml). Standard doses are as follows[1]: 

• Adults and children over 12 years: 10mg once daily 

• Children aged 2-12 years: Usually 5mg once daily if under 30kg; 10mg if over 30kg 

Use the formulation appropriate for age and weight and always follow the instructions on the packaging or given by your doctor or pharmacist. 

How do you take loratadine?

Loratadine is taken once daily, with or without food. Swallow tablets whole with water. The liquid form is measured with a dosing spoon or oral syringe[1]. 

Can you stop taking loratadine?

Yes, you can stop taking it whenever your symptoms settle. It’s often taken only when needed. Loratadine does not require gradual dose reduction and is not habit-forming[1]. 

What do you do if you take too much loratadine?

An accidental overdose of loratadine may cause[1]: 

• Drowsiness 

• Headache 

• Rapid heartbeat 

Seek medical advice if you or someone else takes too much, especially if symptoms are noticeable or persistent. 

What do you do if you forget to take loratadine?

Take the missed dose as soon as you remember. If it's close to the time of your next dose, skip the missed one and continue as normal. Do not take a double dose to make up for a missed tablet[1]. 

How do you store loratadine?

Store your medicine in a cool, dry place away from moisture and direct sunlight. Keep the bottle or blister pack sealed until use, and out of reach of children[1]. 

What medicines can’t you take with loratadine?

Loratadine is usually safe to take alongside most other medicines. However, caution is advised if you are also taking[1]: 

• Antifungals such as ketoconazole 

• Antibiotics such as erythromycin 

• Some heart medication like amiodarone 

• Indigestion medication like cimetidine 

• Any medicine that makes you feel sleepy, gives you dry mouth, or makes it difficult to pee 

Loratadine is safe to take with paracetamol or ibuprofen. Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of loratadine?

Common side effects include[1]: 

• Headache 

• Dry mouth 

• Sleepiness (less common than older antihistamines) 

You should contact your GP if you experience any of these symptoms persistently. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about loratadine

Is loratadine safe for long-term use? 
Yes, it can be used long-term if needed but always check with your doctor if symptoms persist[1]. 

Can I take loratadine every day? 
Yes, once daily is the usual recommended dose for ongoing allergy symptoms[1]. 

Does loratadine make you sleepy? 
It’s considered non-drowsy, but a small number of people may still feel tired. This may be increased if you are taking other medications that also cause drowsiness[1]. 

Can I drink alcohol while taking loratadine? 
Yes, but alcohol may enhance any potential drowsiness[1]. 

Is it safe during pregnancy? 
Only take it if your doctor recommends it[1]. 

Can I combine it with other allergy treatments? 
It is generally ok to take antihistamines with other treatments such as eye drops and nasal sprays, however, speak to your pharmacist first[1]. 

How quickly does it work? 
It usually starts to work within 1 to 3 hours[1]. 

Can it help with skin allergies? 
Yes, it can relieve itching and swelling from skin-related allergic reactions[1]. 

Is loratadine the same as cetirizine? 
No, they’re different antihistamines but treat similar conditions[1]. 

For the official NHS guide to loratadine, visit their website.