Fluticasone Nasal Spray and Drops

What are fluticasone nasal spray and drops?

Fluticasone is a corticosteroid used as a prescription-only nasal spray or drop to treat nasal inflammation. It helps relieve symptoms of allergic rhinitis and nasal polyps. Common brand names include Flixonase, Avamys, and Nasofan[1]. 

You can also find advice on fluticasone inhalers and fluticasone skin cream.

What are fluticasone nasal spray and drops used for?

Fluticasone is used to treat several nasal conditions[1]:

• Fluticasone nasal spray is used for: 

  ○ Allergic rhinitis (hay fever or year-round allergies) 

  ○ Non-allergic rhinitis (e.g. triggered by smoke or pollution) 

• Fluticasone nasal drops are used for: 

  ○ Nasal polyps (small growths inside the nose) 

  ○ Nasal obstruction due to inflammation

How do fluticasone nasal spray and drops work?

Fluticasone works by[1]:

• Reducing inflammation in the nasal passages 

• Suppressing the immune response that causes swelling, itching, and mucus production 

• Improving airflow and reducing symptoms like sneezing, congestion, and runny nose 

Who can take fluticasone nasal spray and drops?

Though suitable for most adults and children over the age of four with a prescription, it may not be suitable for everyone, so check with your doctor first if you[1]: 

• Are allergic to fluticasone or any ingredients in the product 

• Have untreated nasal infections 

• Are taking other steroids 

• Have had nose surgery 

• Pregnant or breastfeeding individuals unless advised by a doctor 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].

What is the typical dosage of fluticasone nasal spray and drops?

Fluticasone comes as a 0.05% nasal spray, a 27.5 microgram nasal spray, or 400 microgram (1mg in 1ml) nasal drops. The typical doses are[1]: 

• Nasal spray: 

  ○ 1 or 2 sprays in each nostril, once or twice daily 

  ○ Maximum dose: 4 sprays per nostril per day 

• Nasal drops: 

  ○ 6 drops in each nostril, once or twice daily 

  ○ Each single-use container contains one full dose 

How do you take fluticasone nasal spray and drops?

Follow the appropriate steps depending on the form[1]: 

Nasal Spray: 

• You may need to prepare the spray, particularly if it is the first time you use it or if it hasn’t been used for a couple days. After shaking and removing the dust cap, prime the spray by pointing it away from you and pumping the spray. 

• Blow your nose gently 

• Close one nostril and insert the nozzle into the other 

• Tilt your head slightly forward and spray while breathing in 

• Repeat for the other nostril 

• Wipe the nozzle and replace the cap 

Nasal Drops: 

• Flick and shake the container to mix 

• Blow your nose gently 

• Bend forward or lie with your head over the edge of a bed 

• Insert the container into one nostril and squeeze until empty 

• Repeat for the other nostril 

• Stay in position for at least 1 minute 

• Discard the container after use 

Consult the product literature for full instructions on how to use them. 

Can you stop taking fluticasone nasal spray and drops?

You may be able to stop using it suddenly if used short-term and symptoms have resolved. If prescribed long-term, speak to your doctor or pharmacist before stopping to avoid symptoms returning[1]. 

What do you do if you take too much fluticasone nasal spray and drops?

Occasional extra doses are unlikely to cause harm. However, long-term overuse may affect your natural steroid hormone production. Contact your pharmacist or doctor if concerned[1]. 

What do you do if you forget to take fluticasone nasal spray and drops?

If you forget a dose[1]:

• Use it as soon as you remember 

• If it’s nearly time for your next dose, skip the missed one 

• Do not double up 

How do I store fluticasone nasal spray and drops?

To store it correctly[1]:

• Keep below 25°C 

• Store nasal drops in the foil pouch and use within 28 days of opening 

• Do not freeze 

• Keep out of reach of children 

What medicines can’t you take with fluticasone nasal spray and drops?

Tell your doctor or pharmacist if you are taking[1]: 

• Ritonavir or cobicistat (HIV medicines) 

• Ketoconazole or itraconazole (antifungals) 

• Other corticosteroids (oral, inhaled, or topical) 

These combinations can increase the risk of side effects. Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of fluticasone nasal spray and drops?

Common side effects occur in around 1 in 100 people and include: 

• A dry or sore nose, or nosebleeds 

• Dry or irritated nose or throat 

• Headache 

• An unpleasant taste or smell 

Rare side effects occur in less than 1 in 10,000 people and include[1]: 

• Cataracts or glaucoma (with long-term use) 

• Nasal septum perforation or damage to your nose 

• Breathing problems 

Your doctor or pharmacist will aim to prescribe the lowest effective dose to reduce risks. You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2].

Frequently asked questions about fluticasone nasal spray and drops

How long does it take to work? 
It can take a few days to a few weeks to feel the full benefit[1]. 

Can I use it long-term? 
Yes, under medical supervision[1]. 

Can I use it during pregnancy? 
Only if advised by your doctor[1]. 

Can I use it with antihistamines? 
Yes, they can be used together if recommended[1]. 

Can I drink alcohol? 
Yes, there is no known interaction[1]. 

Can I use it with other nasal sprays? 
Only if advised by your doctor. You may need to space actuations of each product apart[1]. 

Can I drive after using it? 
Yes, it does not usually affect your ability to drive[1]. 

Can I use it for sinus infections? 
Sometimes, if your doctor prescribes it for that purpose[1]. 

Can I use it for a cold? 
Not usually – it’s intended for allergic or chronic inflammation[1]. 

For the official NHS guide to fluticasone nasal spray and drops, visit their website. 

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