Clotrimazole for Thrush (Canesten)

What is clotrimazole for thrush?

Clotrimazole is an antifungal medicine used to treat infections caused by yeasts and fungi. It’s commonly used to treat thrush, a yeast infection caused by Candida albicans. It’s available under brand names like Canesten and comes in various forms including creams, pessaries, and internal creams. It can be bought in pharmacies and shops, while stronger treatments are only available on prescription[1]. 

You can find advice here on clotrimazole cream, spray, and solution. 

What is clotrimazole for thrush used for?

Clotrimazole is used to treat[1]:

• Vaginal thrush (vulvovaginal candidiasis) 

• Penile thrush (candidal balanitis) 

• External symptoms such as itching, redness, and soreness around the vagina or penis

How does clotrimazole for thrush work?

Clotrimazole works by interfering with the cell membranes of fungi. It stops the fungus from producing ergosterol, an essential component of fungal cell membranes. Without it, the cells become leaky and die, clearing the infection[1]. 

Who can take clotrimazole for thrush?

Clotrimazole can be used over the counter by most adults between the ages of 16 and 60. However, speak to your doctor first if[1]: 

• You are allergic to clotrimazole or other antifungals 

• You are under 16 or over 60 without medical advice 

• It’s the first time you’ve had thrush 

• You have had it more than twice in a six-month period 

• You are a man with thrush but your partner doesn’t have it 

• You have abnormal discharge from your penis 

• You have abnormal discharge or irregular bleeding from your vagina 

• You have sores, ulcers, blisters on your penis or on or around your vagina 

• You are on your period 

• You have symptoms that could indicate a more serious condition (e.g., unusual discharge, sores, or abdominal pain) 

• You are pregnant or breastfeeding  

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].

What is the typical dosage of clotrimazole for thrush?

Clotrimazole pessaries are available in 100mg, 200mg or 500mg strengths. Clotrimazole internal cream contains 500mg of clotrimazole in every 5g of cream. The dose depends on the form and severity of the infection. If prescribed, it is important to follow the instructions given by your doctor or other healthcare professional[1]: 

• Pessaries: 

  ○ 100mg: 1 pessary nightly for 6 nights or 2 pessaries for 3 nights 

  ○ 200mg: 1 pessary nightly for 3 nights 

  ○ 500mg: Single dose 

• Internal Cream: 

  ○ 500mg in 5g cream: Single application 

• External Cream: 

  ○ 1% cream: Apply 2-3 times daily for at least 2 weeks

How do you take clotrimazole for thrush?

The application method depends on the form of clotrimazole used[1]: 

• Pessaries: Insert into the vagina at bedtime using the applicator 

• Internal cream: Insert using the pre-filled applicator 

• External cream: Apply a thin layer to the affected area and rub in gently 

Here are a few additional tips to ensure proper use[1]:

• Wash hands before and after use 

• Avoid using tampons or other vaginal products during treatment 

• Do not use during your period, instead ask your healthcare professional for an alternative if appropriate 

Can you stop taking clotrimazole for thrush?

You should complete the full course even if symptoms improve early. Stopping too soon may allow the infection to return[1]. 

What do you do if you take too much clotrimazole for thrush?

Clotrimazole is unlikely to cause harm if used as directed. If accidentally swallowed or used excessively, seek medical advice[1]. 

What do you do if you forget to take clotrimazole for thrush?

If you forget your dose, apply as soon as you remember. If it’s nearly time for the next dose, skip the missed one. Do not double up to make up for a missed dose[1]. 

How do you store clotrimazole for thrush?

To store clotrimazole safely[1]:

• Store in a cool, dry place 

• Keep out of reach of children 

• Do not use after the expiry date 

What medicines can’t you take with clotrimazole for thrush?

There are a few things to keep in mind when using clotrimazole[1]: 

• It may weaken latex condoms and diaphragms, so use alternative contraception for at least 5 days after use 

• No major drug interactions are known, but always check with a pharmacist if using other topical or oral medications 

• You should also tell your doctor if you’re taking antifungal medicines, tacrolimus, or sirolimus 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of clotrimazole for thrush?

Most people don’t experience side effects, but possible ones include[1]: 

• Mild burning or irritation 

• Redness or itching 

• Lower stomach or pelvic pain 

• Vaginal bleeding 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2].

Frequently asked questions about clotrimazole for thrush

Can I use clotrimazole during pregnancy? 
Yes, but only under medical advice[1]. 

How quickly does clotrimazole work? 
Symptoms often improve within a few days but complete the course[1]. 

Can men use clotrimazole for thrush? 
Yes, for penile thrush[1]. 

Can I have sex while using it? 
It’s best to avoid sex until the infection clears[1]. 

Can I use clotrimazole with other antifungals? 
Usually not necessary – check with a pharmacist[1]. 

What if I keep getting thrush? 
See a GP to rule out underlying causes[1]. 

Can I use clotrimazole on broken skin? 
Avoid applying to broken or irritated skin unless advised[1]. 

Does it affect contraception? 
Yes, it can weaken latex condoms and diaphragms[1]. 

Can I use clotrimazole during my period? 
Using topical treatments for thrush whilst on your period may reduce their effectiveness. Speak to your healthcare provider for an alternative treatment if appropriate[1]. 

For the official NHS guide to clotrimazole, visit their website.

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