Clotrimazole Cream, Spray and Solution

What is clotrimazole?

Clotrimazole is a broad-spectrum antifungal medicine used to treat fungal infections of the skin. Commonly known by the brand name Canesten, it belongs to the imidazole group of antifungals and is available in several topical forms[1]: 

• Cream – for general skin infections 

• Spray – ideal for large or hairy areas 

• Solution – suitable for skin folds, hairy areas, and fungal ear infections 

You can get clotrimazole in a pharmacy, in a shop or on prescription. 

What is clotrimazole used for?

Clotrimazole is used to treat a variety of fungal infections[1]: 

• Athlete’s foot 

• Ringworm 

• Jock itch 

• Fungal skin fold infections (intertrigo) 

• Fungal ear infections (solution only) 

• Thrush (external genital infections) 

How does clotrimazole work?

It works by targeting the structure of fungal cells[1]: 

• Disrupting the fungal cell membrane 

• Preventing the fungus from growing and multiplying 

• Killing the fungus causing the infection 

Who can take clotrimazole?

This medicine is generally safe for most adults and children, but you should speak to a doctor or pharmacist first if[1]: 

• You are allergic to clotrimazole or any ingredients in the product 

• You are pregnant, trying to get pregnant, or are breastfeeding 

The spray is not suitable for babies under 4 weeks with open wounds or large areas of broken or damaged skin. 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

What is the typical dosage of clotrimazole?

Clotrimazole comes as a 1% strength cream, spray or solution. Dosage varies depending on the form used[1]: 

• Cream: Apply 2-3 times daily for at least 2 weeks (up to 4 weeks for athlete’s foot) 

• Spray: Apply 2-3 times daily from a distance of about 15cm 

• Solution: 

• Skin: Apply 2-3 times daily 

• Ear: Use 2-3 drops in the ear 2-3 times daily 

To prevent recurrence, it’s important to continue treatment for at least two weeks after symptoms clear, sometimes up to four weeks if recommended. Speak to your GP if the infection has not cleared after 4 weeks, longer use can lead to resistance and you may need an alternative treatment[1]. 

How do you use clotrimazole?

Follow these steps for correct application[1]: 

• Wash and dry the affected area thoroughly 

• Apply a thin layer of cream, spray, or solution 

• Rub in gently (except for ear use) 

• Wash hands after application 

• Avoid covering with dressings unless advised 

If the area affected is large or hairy, use the spray or the solution. If the area is on your feet, take care to wash and dry thoroughly between the toes[1]. 

Can you stop taking clotrimazole?

No. Complete the full course even if symptoms improve early. Stopping too soon may cause the infection to return[1]. 

What do you do if you take too much clotrimazole?

Excessive use can lead to skin irritation. if this occurs take care to use less on the next application. If accidentally swallowed or gets into the eyes, seek medical advice[1].

What do you do if you forget to take clotrimazole?

If you forget to apply a dose[1]: 

• Apply as soon as you remember 

• If it’s nearly time for the next dose, skip the missed one 

• Do not double up 

How do I store clotrimazole?

To keep the medicine effective[1]: 

• Store below 25°C 

• Keep in original packaging 

• Keep out of reach of children 

• Do not use after the expiry date 

What medicines can’t you take with clotrimazole?

There are a few important interactions to note[1]: 

• Avoid using with Sofradex ear drops (may cause a heat reaction) 

• May reduce the effectiveness of latex contraceptives (e.g. condoms, diaphragms) – use alternative contraception for at least 5 days after use 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of clotrimazole?

Most side effects are mild, but some can be serious. The most common side effects include[1]: 

• Mild burning or stinging 

• Redness or irritation 

You should contact your GP if you experience any of these symptoms and they do not go away. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about clotrimazole

How long does clotrimazole take to work? 
Symptoms usually improve within a few days. It can take between 1-4 weeks to completely clear the infection. If symptoms show no improvement in 7 days, speak to your GP so they can review your treatment[1]. 

Can I use clotrimazole during pregnancy? 
Yes but consult your doctor first[1]. 

Can I use clotrimazole while breastfeeding? 
Yes, but you should be careful that your baby does not come into contact with the treated areas, and wash your hands before picking up your baby[1]. 

Can I use it on broken skin? 
No – avoid unless advised by a doctor or pharmacist[1]. 

Can I use clotrimazole with other antifungals? 
Only if recommended by your doctor or pharmacist[1]. 

Can I use it on my face? 
Only under medical supervision[1]. 

Can I use it for vaginal thrush? 
Yes, for external symptoms – internal treatment may also be needed[1]. 

For the official NHS guide to clotrimazole, visit their website.