Cinnarizine

What is cinnarizine?

Cinnarizine is a drowsy antihistamine that can treat balance issues and nausea. For that reason, it is used for travel sickness, vertigo, and inner ear disorder symptoms. It can be found under brand names including Stugeron and is available on prescription or can be bought in pharmacies[1]. 

What is cinnarizine used for?

Cinnarizine is used to treat a range of balance and nausea conditions, including travel sickness, , vertigo, tinnitus, Ménière’s disease, and nausea and vomiting caused by inner ear problems. It can also come mixed with dimenhydrinate to treat vertigo[1]. 

How does cinnarizine work?

Cinnarizine works in two main ways. First, it blocks histamine receptors in the brain, which helps reduce feelings of nausea and vomiting. It also improves blood flow in the inner ear, which helps to relieve balance problems and dizziness[1]. 

Who can take cinnarizine?

Cinnarizine can be taken by most adults and children aged 5 years and over. However, in some cases, it may not be suitable for people who have[1]: 

• An allergy to cinnarizine or any of the ingredients listed as part of the medication  

• Parkinson’s disease 

• Liver or kidney problems 

• Porphyria (a hereditary blood disorder) 

• Problems peeing or emptying your bladder  

• Epilepsy or any health condition that causes fits or seizures 

• Glaucoma (increased pressure in the eye) 

• An allergy test in the near future 

• Been trying to get pregnant, are pregnant, or are breastfeeding 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

How do you take cinnarizine?

When you take cinnarizine, you can swallow the tablets whole with water, or suck or chew them. It’s best to take cinnarizine after meals to help reduce stomach upset – following the dosage instructions provided by your doctor or pharmacist[1]. 

What is the typical dosage of cinnarizine?

Cinnarizine comes as 15mg tablets. The typical dose of cinnarizine depends on the condition being treated. For motion sickness, most adults and children aged 12 and over should have 2 tablets (30mg in total) two hours before travelling, then 1 tablet every 8 hours if needed. Younger children will be given a reduced dose, usually 1 tablet (15mg) two hours before travel, then half a tablet every 8 hours if needed[1]. 

For other problems (such as vertigo or Ménière’s disease), the usual dosage for adults and children aged 12 and over is 2 tablets (30mg) three times a day. Again, children aged 5 to 11 years will have a reduced dose, usually 1 tablet three times a day. Your doctor or pharmacist will advise on the best dosage for your personal circumstances[1]. 

Can you stop taking cinnarizine suddenly?

For travel sickness, you can stop taking cinnarizine right after your trip. If you’re using it for inner ear issues, consult your doctor or pharmacist before stopping to avoid symptom recurrence[1]. 

What should you do if you take too much cinnarizine?

Taking too much cinnarizine may cause a range of symptoms, such as severe drowsiness or confusion, nausea or vomiting, a fast or irregular heartbeat, or seizures – especially in children. If you think you or someone else has taken too much cinnarizine, contact your doctor or NHS 111 immediately. If you need to go to A&E do not drive. Ask someone to drive you or call 999 and ask for an ambulance.  Take the medicine packaging with you so that the healthcare staff know exactly what you’ve taken[1]. 

What should you do if you forget a dose of cinnarizine?

If you forget a dose of cinnarizine, take it as soon as you remember, unless it is nearly time for your next dose. Do not take a double dose to make up for a missed one, and always leave at least 8 hours between doses (or as advised on your medicine label or packaging)[1]. 

What medicines should you avoid while taking cinnarizine?

It’s advisable to avoid taking cinnarizine with any of the following[1]: 

• Other antihistamines that cause drowsiness 

• Any medication that gives you a dry mouth or makes it difficult for you to pee 

• Sleeping tablets or tranquilisers 

• Certain antidepressants and antipsychotics   

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of cinnarizine?

The most common side effects when you take cinnarizine are[1]: 

• Drowsiness 

• A dry mouth 

• Upset stomach 

• Weight gain (with long-term use) 

More serious side effects are rare, and you should seek urgent medical attention if you experience any of the following[1]:  

• Tremors of stiffness, especially in older adults 

• Joint pains and a red skin rash 

• Jaundice (yellowing of the skin or eyes) or dark urine can be sings of liver problems  

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about cinnarizine

Is cinnarizine safe for long-term use? 

Cinnarizine may be safe for you to use over extended periods, but long-term use should be monitored by a medical professional for your safety[1]. 

Can I drive after taking cinnarizine? 

Cinnarizine can make you feel drowsy. If it does, avoid driving until you feel better[1]. 

Is cinnarizine addictive? 

No, cinnarizine is not usually habit-forming, but if you have concerns speak to a medical professional[1]. 

Can I take cinnarizine with paracetamol or ibuprofen? 

Yes, taking cinnarizine with paracetamol or ibuprofen is generally safe, but check with a pharmacist and do not exceed daily doses[1]. 

Does cinnarizine help with anxiety? 

No, cinnarizine is not used to treat anxiety in most cases[1]. 

Can I drink alcohol while taking cinnarizine? 

It is best to avoid alcohol, as it can increase drowsiness caused by cinnarizine[1]. 

Is cinnarizine available over the counter? 

You can usually get cinnarizine without a prescription for travel sickness in adults and children over 5 years old. Other uses may require a prescription, though. Speak to a pharmacist if you are unsure[1]. 

Can I take cinnarizine while pregnant? 

Cinnarizine is not usually recommended during pregnancy, and you shouldn’t take it unless advised by your doctor. [1]. 

How quickly does cinnarizine work? 

Cinnarizine usually works within two hours – do not exceed the recommended dose if you don’t feel its results this quickly[1]. 

Can children take cinnarizine? 

Yes, children aged five years and over can usually safely take cinnarizine, as advised by a doctor or pharmacist[1]. 

For the official NHS guide to cinnarizine, visit their website.