Vydura (rimegepant)

The active ingredient in Vydura is rimegepant. It works by blocking CGRP, a chemical in your body that triggers migraine pain signals.

You have two options with Vydura:

1. Take it when you feel a migraine starting to stop it from developing.

2. Use it every other day to prevent migraines if you get them frequently.

Research shows rimegepant works well for both treating and preventing migraines.

In studies of rimegepant for migraine treatment:

• 59% of people felt pain relief within 2 hours

• 21% became completely pain-free within 2 hours

• 35% no longer experienced their most troublesome symptom within 2 hours

• 42% continued to feel relief between 2-48 hours after taking it

• 86% of people didn't need additional pain relief in the first 24 hours

For migraine prevention, a different study found:

• People experienced 4.3 fewer monthly migraine days on average

• Users saw a 50% reduction in their monthly migraine days

For treating a migraine attack, simply place one wafer under your tongue and let it dissolve. You don't need to take it with food or water and, if needed, you can take another wafer. But you must wait 24 hours before you do.

If you're using Vydura to prevent migraines, you can take one wafer every other day. Remember though, never take more than one Vydura wafer within a 24-hour period.

Although it’s possible to experience side effects when you use Vydura (rimegepant), it’s highly unlikely. The most common is nausea and a single clinical trial noted a small possibility of urinary tract infection (UTI) and dizziness. In very rare cases, Vydura might cause a rash or shortness of breath, which could indicate an allergic reaction.