Skip to main content


Buy Alli at

Although we no longer stock this product, you can save 10% when you place your order with our sister company Chemist Direct

Use code 10NEWCD for 10% off your first order*

Shop now

*Excludes Slimfast, Regaine, Nicorette and baby milk

What is Alli?

Alli is an over-the-counter weight loss medicine that contains orlistat, an active ingredient designed to target fat in your digestive system.

What are the key benefits of Alli?

Alli is unique in that it is a licensed medicine, rather than a supplement or complementary remedy. It contains a clinically proven ingredient which has been available for doctors to prescribe for over 10 years, under the brand name "Xenical", and is now available as a non-prescription medicine. Alli is the only clinically proven, pharmacy only weight-loss medicine in the UK, and GSK, the manufacturers of Alli, claims that a by taking the product, and by consuming a healthy, calorie-restricted diet, you can lose up to 50% more weight than you will without it.

How does Alli work?

Alli works by preventing approximately 25% of the fat you consume from being absorbed when used alongside a reduced-calorie and low-fat diet.

Alli is a weight-loss aid, an aid and not a miracle worker. It does not claim to help you to miraculously lose weight while living the lifestyle that you want to. The Alli weight loss solution facilitates the use of pills and healthy lifestyle changes combined.

How do I use Alli?

Alli is available in various package sizes such as Alli 84 and Alli 42, there is no difference in the product between the pack sizes other than the one contains more tablets. Further information is available on the products micro-site.

With Alli, weight loss is going to mean changing your diet from unhealthy to healthy, from over- sized portions to regular portions, from no exercise to regular exercise. Losing weight by taking Alli means making the correct healthy lifestyle changes in order to lose weight the right way.

Alli is taken just before, with, or within an hour of each main meal. If a meal is missed or contains no fat, there’s no need to take one.

Alli should not be taken for a period of longer than six months – or three months if there are no noticeable effects and you find it’s not helping with your weight loss.

It’s recommended that multivitamin supplement is taken during a course of Alli, preferably at bedtime.

Is Alli suitable for me?

Alli is intended for adults (over 18 years old) who have a BMI over 28. Speak with your doctor about use of Alli if you already take certain medicines (including ciclosporin, amiodarone, acarbose, or warfarin or other anticoagulants) and have existing medical conditions (including chronic malabsorption syndrome, or cholestasis).

Individuals with high blood pressure, or women who take the oral contraceptive pill, should also consult a pharmacist or doctor before starting a course of Alli.

What are the side effects of Alli?

Like all medicines, use of Alli may bring on side effects, although not everybody will experience them.

Common side effects include:

  • Wind
  • Sudden and frequent bowel movements
  • Fatty/oily stools

If Alli is taken correctly, and you stick to your recommended fat target, you will likely reduce the possibility of the above side effects. Eating too much fat increases the chances of experiencing these.

We’ve joined forces with, a GPhC registered (9010315) online pharmacy - rated as 'excellent' on Trustpilot

Free UK delivery On orders over £40+

Trust Pilot rating based on over 45,000 reviews

Based on 45,000+ reviewsas of August 2019

+Orders below £40 will incur a £3.95 delivery charge. Delivered within five working days. Delivered Mon-Fri (excluding weekend and bank holidays). Additional terms and conditions apply, please click here.