Ranitidine
What is ranitidine?
Ranitidine is a medicine that was used to reduce the amount of acid produced in the stomach. It belonged to a group of drugs called H2-receptor antagonists, or H2 blockers. Ranitidine was commonly used to relieve symptoms caused by excess stomach acid, such as heartburn and ulcers.
However, it has now been withdrawn from use due to safety concerns that it contained a small amount of an impurity that has been linked to an increased risk of cancer in animals[1].
What was ranitidine used for?
Before its withdrawal, ranitidine was widely prescribed or bought over the counter to treat and prevent a range of acid-related digestive issues, including[1]:
Indigestion and heartburn
Acid reflux and gastro-oesophageal reflux disease (GORD)
Stomach and duodenal ulcers
Zollinger-Ellison syndrome – a rare condition that causes excessive acid production
To get help for the conditions ranitidine was used for please visit these pages:
Frequently asked questions about ranitidine
Why was ranitidine withdrawn?
It was removed from the market due to the presence of NDMA, a probable human carcinogen. This applies to the UK and globally[1].
Is ranitidine safe to use now?
No. Ranitidine is no longer recommended or available in the UK[1].
What are alternatives to ranitidine?
Proton pump inhibitors (PPIs) like omeprazole and lansoprazole are commonly used alternatives[1].
Can I still buy ranitidine over the counter?
No, it is no longer sold or prescribed[1].
Will ranitidine return to the market?
It’s uncertain. Reformulated versions without NDMA contamination may be considered in the future, but for now it remains unavailable[1].
For the official NHS guide to ranitidine, visit their website.
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The information provided on this Medicines A-Z page is intended for general informational purposes only and was accurate as of June 2025. It is designed to offer simple, patient-friendly summaries of prescribed medications based on publicly available resources, including those from the National Health Service (NHS). This content does not constitute medical advice, diagnosis, or treatment and is not a substitute for professional guidance from a qualified healthcare professional, such as a doctor or pharmacist.
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References
Have an existing NHS prescription?
