Pepto-Bismol

What is Pepto-Bismol?

Pepto-Bismol is an over-the-counter medicine used to relieve a range of digestive symptoms including heartburn and acid reflux. It contains the active ingredient bismuth subsalicylate and is available in liquid and chewable tablet forms. It is sold under brand names such as Pepto-Bismol and Pepti-Calm[1].

What is Pepto-Bismol used to treat?

Pepto-Bismol provides short-term relief for several common digestive complaints, including[1]:

• Heartburn and acid reflux 

• Indigestion 

• Diarrhoea 

• Nausea (feeling sick)  

How does Pepto-Bismol work?

Bismuth subsalicylate helps settle the stomach and relieve digestive discomfort by[1]:

• Coating the stomach lining to protect it from stomach acid 

• Acting as a mild antacid to reduce acidity 

• Providing anti-inflammatory and antibacterial effects in the digestive tract 

Who can take Pepto-Bismol?

This medicine is suitable for most adults and teenagers over the age of 16. You should speak to your doctor or pharmacist before you take Pepto-Bismol if you[1]: 

• Are allergic to aspirin, bismuth salicylate, or any of Pepto-Bismol's other ingredients 

• Have a bleeding disorder 

• Have diabetes, gout, or a rare condition called phenylketonuria 

• Are taking blood-thinning medication or other conflicting drugs such as tetracyclines 

• Are under 16 years of age, due to the risk of Reye’s syndrome 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].

What is the typical dosage of Pepto-Bismol?

Standard dosing instructions for adults and children over 16 are[1]:

• Take up to 2 tablets or 30ml of the liquid every 30 to 60 minutes as needed 

• Do not exceed 8 doses in 24 hours and do not take for more than 2 days 

• Always follow the guidance on the packaging or as directed by a pharmacist

How do you take Pepto-Bismol?

You can take Pepto-Bismol with or without food. When using the medicine[1]:

• Chew the tablets thoroughly before swallowing 

• Shake the liquid bottle well before each dose 

• Use a measuring cup or spoon to ensure correct dosing 

Can you stop taking Pepto-Bismol?

Yes, you can stop once your symptoms have resolved. It’s designed for short-term use only. If symptoms persist for more than two days, speak to your doctor or pharmacist[1].

What do you do if you take too much Pepto-Bismol?

Taking more than the recommended amount can lead to increased risk of side effects such as[1]: 

• Ringing in the ears (tinnitus) 

• Dizziness or confusion 

• Feeling sick 

If you or someone else may have overdosed, seek immediate medical attention or call NHS 111.

What do you do if you forget to take Pepto-Bismol?

Pepto-Bismol is taken as needed, not on a fixed schedule. If you forget a dose, simply wait until you need it again. Do not take more than 8 doses in 24 hours[1]. 

How do you store Pepto-Bismol?

Keep Pepto-Bismol[1]:

• In a cool, dry place 

• Away from heat and direct sunlight 

• Out of reach of children 

• Within its expiry date, and discard any leftover liquid after that time

What medicines can’t you take with Pepto-Bismol?

Avoid using Pepto-Bismol alongside[1]:

• Aspirin, ibuprofen, or other salicylate-containing medicines 

• Anticoagulants like warfarin 

• Diabetes medication 

• Tetracyclines such as, doxycycline, or minocycline 

• Medicines for gout

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of Pepto-Bismol?

Common and usually harmless side effects of Pepto-Bismol include[1]: 

• Temporary blackening of the tongue or stools 

• Mild constipation 

• Nausea 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about Pepto-Bismol

Can I take Pepto-Bismol with food? 
Yes, it can be taken with or without food[1]. 

How quickly does it work? 
Most people feel better within 30 to 60 minutes[1]. 

Is it safe to use during pregnancy or breastfeeding? 
No, it’s not recommended – ask your doctor for advice[1]. 

Can children take Pepto-Bismol? 
It’s only for those aged 16 or older[1]. 

Why do my tongue and stools look black after taking it? 
This is a harmless and temporary side effect caused by bismuth[1]. 

Is it safe to take daily? 
No, it’s intended for short-term use only[1]. 

Can I take it with paracetamol? 
Yes but avoid taking it with aspirin or ibuprofen[1]. 

Is it okay to use if I have kidney problems? 
You should consult your doctor before use[1]. 

Can I drink alcohol while taking pepto-bismol? 
It's best to avoid alcohol, especially if you’re treating an upset stomach[1]. 

For the official NHS guide to Pepto-Bismol, visit their website. 

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