Mometasone nasal spray

What is mometasone?

Mometasone nasal spray is a corticosteroid medicine used to reduce inflammation in the nasal passages. It contains mometasone furoate and helps relieve common symptoms such as sneezing, nasal congestion, runny nose, and itching. You can get it on prescription or buy it in a pharmacy. It is commonly known by brands names Clarinaze and Nasonex[1]. 

What is mometasone used for?

Doctors commonly prescribe mometasone nasal spray for conditions involving nasal inflammation, including[1]:

  • Allergic rhinitis (both seasonal hay fever and year-round allergies) 

  • Nasal polyps (in adults) 

  • Acute rhinosinusitis (short-term sinus infections, sometimes under specific NHS guidelines) 

How does mometasone work?

Mometasone is a topical corticosteroid that works locally inside the nose. It helps by[1]:

  • Reducing inflammation and swelling in the nasal lining 

  • Helping clear nasal congestion 

  • Relieving sneezing, itching, and a runny nose 

Who can take mometasone?

Mometasone nasal spray is suitable for[1]: 

  • Adults and children aged 3 years and older (for allergic rhinitis and hay fever) 

  • Adults aged 18 and over (for nasal polyps) 

However, it is not suitable for people with[1]: 

  • An allergy to mometasone or any ingredient listed in the spray 

  • Untreated nasal infections such as herpes simplex 

  • Recent nasal surgery or injury (until fully healed) 

  • Recent history of steroid medication (oral or injection)  

  • A history of tuberculosis, glaucoma, or cataracts 

  • Cystic fibrosis 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].

What is the typical dosage of mometasone?

Mometasone nasal spray comes in a strength of 50 micrograms. Mometasone 25 microgram nasal spray is combined with an antihistamine called olopatadine known as Ryaltris. Dosage depends on the condition being treated and the patient's age[1]: 

  • For allergic rhinitis (adults): 1 to 2 sprays in each nostril once daily. This may be reduced to 1 spray once symptoms are under control, and you should never use more than 2 sprays in 24 hours 

  • For nasal polyps (adults): 1 to 2 sprays in each nostril once daily, increasing to twice daily if needed, and you should never use more than 4 sprays in 24 hours 

Children will take a reduced dosage. 

Always follow your pharmacist or doctor’s instructions or the directions in the patient leaflet.

How do you take mometasone?

Proper technique is important for effectiveness, read the Patient Information Leaflet for full directions on how to use your medicine[1]: 

  • If you are using the spray for the first time or after a break of 14 days or more, you will need to ‘prime’ the bottle 

  • Shake the bottle gently 

  • Blow your nose to clear the nostrils 

  • Close one nostril and insert the nozzle into the other 

  • Spray while gently breathing in through your nose 

  • Repeat the process for the other nostril 

  • Wipe the nozzle clean and replace the cap 

It may take a few days for the full benefit to be felt. 

Can you stop taking mometasone?

Yes, but with caution[1]:

  • If you’ve only been using it for a short period, stopping is usually fine 

  • If used long-term, don’t stop suddenly without medical advice 

  • Symptoms may return if the spray is stopped too early, so consult your doctor or pharmacist first

What do you do if you take too much mometasone?

Accidentally using more than prescribed is unlikely to be dangerous in the short term. However[1]:

  • Long-term overuse can increase the risk of side effects 

  • If you’re concerned about overuse, speak to your doctor or pharmacist 

What do you do if you forget to take mometasone?

If you forget to use your nasal spray[1]:

  • Take the missed dose as soon as you remember 

  • If it’s close to your next scheduled dose, skip the missed one 

  • Never take a double dose to make up for a forgotten dose 

What medicines can’t you take with mometasone?

Some medicines may increase the risk of side effects if taken with mometasone. Speak to your doctor if you take[1]: 

  • Other corticosteroids (whether oral, inhaled, or injectable) 

  • Ritonavir or cobicistat (used for HIV) 

  • Ketoconazole (an antifungal medicine) 

Note this is not a complete list, always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of mometasone?

Side effects are usually mild but can occur. Common side effects include[1]: 

  • Headache 

  • Sneezing or irritation in the nose 

  • Nosebleeds 

  • Sore throat 

  • Unpleasant taste or smell 

  • Respiratory tract infection 

Rare but more serious side effects may include[1]: 

  • Eye problems, such as blurred vision or glaucoma 

  • Slowed growth in children (with long-term use) 

  • Nose pain or nosebleeds that don’t stop 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1] 

  • Difficulty breathing  

  • Tightness in throat and chest  

  • Swelling of the tongue or throat  

  • Feeling faint or dizzy  

  • Blue/grey skin or lips  

  • Loss of consciousness 

 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2].

Frequently asked questions about mometasone

How long does mometasone take to work? 
You may notice relief within 12 to 48 hours, but full effects can take a few days[1]. 

Can I use mometasone long-term? 
Yes, it can be used long-term, but only under regular medical supervision[1]. 

Can I drink alcohol while using mometasone? 
Yes, alcohol does not interact with mometasone nasal spray[1]. 

Does mometasone nasal spray cause drowsiness? 
No, it does not cause drowsiness and is safe to use during the day[1]. 

For the official NHS guide to mometasone nasal spray, visit their website. 


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The information provided on this Medicines A-Z page is intended for general informational purposes only and was accurate as of June 2025. It is designed to offer simple, patient-friendly summaries of prescribed medications based on publicly available resources, including those from the National Health Service (NHS). This content does not constitute medical advice, diagnosis, or treatment and is not a substitute for professional guidance from a qualified healthcare professional, such as a doctor or pharmacist.

Patients should always consult their healthcare professional before starting, stopping, or changing any prescribed medication, and must inform them of any known allergies, medical conditions, or other medications being taken to ensure safe use. The inclusion of a medication on this page does not guarantee its availability, suitability, or approval for use in all cases, as prescribing decisions are made by healthcare professionals based on individual patient needs.

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