Mometasone Inhalers

What are mometasone inhalers?

Mometasone inhalers are prescription-only corticosteroid preventer inhalers used to reduce airway inflammation in people with asthma. They are not suitable for treating sudden breathing difficulties as they do not work immediately. Common brands include Asmanex Twisthaler and combination inhalers such as Enerzair[1]. 

What are mometasone inhalers used for?

These inhalers are prescribed for[1]: 

  • Asthma in adults and adolescents aged 12 or older 

  • Chronic asthma that is not controlled by other treatments 

How do mometasone inhalers work?

Mometasone works by reducing inflammation and swelling in the airways to try and help prevent asthma attacks. This leads to[1]: 

  • Fewer asthma symptoms like wheezing and coughing 

  • Improved lung function over time 

It must be used regularly and is not intended for rapid relief of asthma attacks. 

Who can take mometasone inhalers?

These inhalers are suitable for[1]: 

  • Adults and adolescents aged 12 years or older 

They may not be suitable for[1]: 

  • People allergic to mometasone or other steroids or any other ingredient listed in your medicine  

  • People who have come into contact with anyone with a viral infection like shingles, chickenpox, or measles 

  • Those with active infections such as TB or herpes  

  • Develop thrush (white patches) in your mouth or throat whilst using treatmentChildren under 12 years (unless prescribed by a specialist) 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

How do you take mometasone inhalers?

Follow the steps listed in the Patient Information Leaflet for correct use[1]: 

  • Remove the cap by twisting it off 

  • Sit or stand upright 

  • Exhale fully 

  • Place the mouthpiece in your mouth and inhale deeply and quickly 

  • Hold your breath for 10 seconds or as long as feels comfortable 

  • Replace the cap to load the next dose 

  • Rinse your mouth after each use to prevent oral thrush 

You can watch instructional videos on how to use mometasone inhalers on RightBreathe. 

What is the typical dosage of mometasone inhalers?

Mometasone inhalers come in two strengths: 200micrograms or 400micrograms in each puff. The prescribed dose depends on the individual’s condition, but the usual dose is 1 or 2 puffs, once or twice a day. Once symptoms are under control, your doctor or pharmacist may reduce the dose[1]. When using a combination inhaler such as Enerzair, strength and dose will differ, Enerzair is normally taken once a day.  

Can you stop taking mometasone inhalers?

Do not stop taking mometasone suddenly, especially if you are taking high doses of steroids as may lead to adrenal crisis. Your doctor may recommend tapering the dose gradually, because stopping too soon may lead to worsening asthma symptoms[1].  

What do you do if you take too much mometasone inhalers?

Taking too much occasionally is not usually harmful. Long-term overuse may cause[1]: 

  • Adrenal suppression 

  • Cushing’s syndrome 

  • Bone thinning 

Speak to your doctor or pharmacist if you’re concerned. 

What do you do if you forget to take mometasone inhalers?

If you miss a dose[1]: 

  • Take it as soon as you remember 

  • Skip it if it’s nearly time for your next dose 

  • Do not double up 

How do I store mometasone inhalers?

Proper storage keeps the inhaler safe and effective[1]: 

  • Store below 25°C 

  • Keep the inhaler dry – do not wash it 

  • Keep out of reach of children  

  • Use within 3 months of opening 

What medicines can’t you take with mometasone inhalers?

Tell your doctor if you take[1]: 

  • Other corticosteroids (can increase steroid effects) including other inhalers, eczema creams, steroid tablets or injections, nasal sprays, eye drops, or nose drops 

  • Antifungal medicines such as ketoconazole or itraconazole 

  • Antiviral medicines like ritonavir or cobicistat 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of mometasone inhalers?

These inhalers can cause some side effects, particularly when used long-term.  

Common[1]: 

  • Hoarse voice or sore throat 

  • Oral thrush (white patches in the mouth) 

  • Headaches 

Serious but rare[1]: 

  • Moon face or weight gain in back or belly as a sign of Cushing’s syndrome 

  • Eye problems (e.g. cataracts or glaucoma) 

  • Adrenal gland issues (fatigue, low blood pressure) 

  • Slowed growth in children 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1] 

  • Difficulty breathing  

  • Tightness in throat and chest  

  • Swelling of the tongue or throat  

  • Feeling faint or dizzy  

  • Blue/grey skin or lips  

  • Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about mometasone inhalers

How long do mometasone inhalers take to work? 
Usually within 3-7 days. Full benefits may take a few weeks[1]. 

Can I use mometasone inhalers during an asthma attack? 
No – use your reliever inhaler instead[1]. 

Do I need to rinse my mouth after use? 
Yes – to prevent thrush[1]. 

Can I use mometasone inhalers with other inhalers? 
Yes – especially with reliever inhalers[1]. If you are using a combination inhaler, your doctor may stop other inhalers as it may contain a corticosteroid, antimuscarinic and a long-acting beta agonist. 

Is it safe during pregnancy? 
Generally yes but check with your doctor if you have concerns[1]. 

Can I drive or cycle? 
Yes, unless you have visual side effects[1]. 

Does mometasone inhalers affect growth in children? 
Rarely – but height and weight should be monitored if treatment is prolonged[1]. 

Do I need a steroid card? 
Possibly – ask your doctor or pharmacist if you’re on high doses[1]. 

Can I stop if I feel better? 
No – mometasone is a preventer inhaler continue using it as prescribed to keep symptoms controlled[1]. 

For the official NHS guide to mometasone inhalers, visit their website. 


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The information provided on this Medicines A-Z page is intended for general informational purposes only and was accurate as of June 2025. It is designed to offer simple, patient-friendly summaries of prescribed medications based on publicly available resources, including those from the National Health Service (NHS). This content does not constitute medical advice, diagnosis, or treatment and is not a substitute for professional guidance from a qualified healthcare professional, such as a doctor or pharmacist.

Patients should always consult their healthcare professional before starting, stopping, or changing any prescribed medication, and must inform them of any known allergies, medical conditions, or other medications being taken to ensure safe use. The inclusion of a medication on this page does not guarantee its availability, suitability, or approval for use in all cases, as prescribing decisions are made by healthcare professionals based on individual patient needs.

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