Lymecycline

What is lymecycline?

Lymecycline is a type of antibiotic that belongs to the tetracycline family and is mainly used to treat bacterial infections, particularly acne. It is available under the brand name Tetralysal 300[1]. 

What is lymecycline used to treat?

It’s commonly prescribed for[1]: 

• Acne (especially moderate to severe types) 

• Chest infections 

• Urinary tract infections (UTIs) 

• Sexually transmitted infections, such as chlamydia 

• Eye and skin infections 

How does lymecycline work?

Lymecycline stops bacteria from growing by preventing them from making essential proteins. This helps your body’s immune system fight off the infection more effectively[1]. 

Who can take lymecycline?

Lymecycline is generally suitable for most people, but not everyone can take it safely[1]. 

It’s suitable for adults and children over 12 years old. It’s not suitable for[1]: 

• Children under 12 (due to risk of tooth discolouration and bone effects) 

• People with allergies to tetracycline antibiotics 

• Those with liver or kidney problems Pregnant or breastfeeding women Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

What is the usual dosage of lymecycline?

The dose depends on the condition being treated, but for acne, the standard dose is[1]: 

• 1 capsule (408mg) once daily, usually taken in the morning 

• For other infections, dosing may vary – follow your doctor’s instructions 

• Acne treatment typically lasts for at least 8 weeks 

How to take lymecycline

To get the best results and avoid stomach irritation, take it as follows[1]: 

• Swallow with a full glass of water 

• Can be taken with or without food 

• Do not lie down straight after taking it 

• Avoid taking it with milk, antacids, or supplements containing calcium, magnesium, or iron 

Can you stop taking lymecycline early?

No, you should complete the full course, even if you start feeling better. Stopping early may cause the infection to come back or become harder to treat[1]. 

What if I take too much lymecycline?

Taking more than the recommended dose may cause[1]: 

• Nausea or vomiting 

• Kidney issues (in high doses) 

Call NHS 111 or contact your doctor if this happens. 

What if I forget a dose of lymecycline?

If you forget your dose[1]: 

• Take it as soon as you remember 

• If it’s almost time for your next dose, skip the missed one 

• Do not take two capsules to make up for a missed dose 

Medicines to avoid while taking lymecycline

Some products can interfere with how lymecycline works. Avoid taking it at the same time as[1]: 

• Antacids (Take 1 hour before or 2 hours after antacids)Iron or calcium supplements 

• Dairy products (e.g. milk, yoghurt) (Take 1 hour before or 2 hours after dairy products) 

• Oral retinoids (e.g. isotretinoin for acne) 

• Warfarin (may increase bleeding risk) 

• Combined oral contraceptives (effectiveness may be reduced if you have vomiting or diarrhoea – use extra protection like condoms) 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of lymecycline?

Like all medicines, lymecycline can cause side effects. Most are mild, but some are more serious[1]. 

Common side effects include[1]: 

• Headache 

• Feeling sick (nausea) 

• Diarrhoea 

Rare but serious side effects include[1]: 

• Severe allergic reactions (rash, swelling, difficulty breathing) 

• Liver or kidney issues 

• Photosensitivity – increased risk of sunburn (Avoid direct sunlight/tanning beds, use SPF 50+ even on cloudy days) 

• Oesophageal irritation or ulcers – avoid lying down after taking the capsule 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about lymecycline

Can I drink alcohol while taking lymecycline? 
Yes, in moderation. Alcohol doesn’t directly affect lymecycline[1]. 

Can I go in the sun while on lymecycline? 
Be careful – this medicine can make your skin more sensitive. Wear sunscreen and avoid tanning beds[1]. 

Will lymecycline affect my contraception? 
It shouldn't directly, but if you experience vomiting or diarrhoea, use additional contraception like condoms[1]. 

Can I have vaccinations while taking lymecycline? 
Some antibiotics affect vaccines such as cholera and oral typhoid vaccine. Speak to your doctor or pharmacist about when it’s safe to take lymecycline if you’re due to have a vaccine[1]. 

Will lymecycline give me thrush? 
Sometimes, a course of antibiotics such as lymecycline can kill the harmless bacteria that defend against thrush. Speak to your doctor or pharmacist if you’re worried[1]. 

Can I take lymecycline long-term? 
For acne, it may be prescribed for several months. Your doctor will monitor your progress[1]. 

For the official NHS guide for lymecycline, visit their website.