Hydrocortisone for Piles and Itchy Bottom

What is hydrocortisone for piles and itchy bottom?

Hydrocortisone is a mild corticosteroid used to relieve inflammation, itching, and discomfort in the anal area. It is available in a variety of forms for both internal and external use, with some preparations available to bur from a pharmacy, and others only available on prescription. Forms include[1]

  • Creams and ointments 

  • Suppositories 

  • Rectal sprays 

Common brand names include Anusol HC, Anugesic-HC, Uniroid, Proctosedyl, and Xyloproct[1]

You can also find advice on hydrocortisone, hydrocortisone buccal tablets, hydrocortisone for skin, hydrocortisone injections, hydrocortisone rectal foam, and hydrocortisone tablets

What is hydrocortisone used for?

Hydrocortisone products are used to relieve symptoms of[1]

  • Haemorrhoids (piles), both internal and external 

  • Pruritus ani (persistent itching around the anus) 

  • Inflammation or irritation of the anal region 

Some products also contain a local anaesthetic such as cinchocaine hydrochloride to reduce pain.

How does hydrocortisone work?

Hydrocortisone works locally to calm inflammation in the affected area. Specifically, it[1]

  • Reduces swelling and redness 

  • Suppresses immune reactions in the skin 

  • Relieves itching and general discomfort 

When combined with a local anaesthetic, it also provides targeted pain relief.

Who can take hydrocortisone?

This medicine is suitable for most adults but not for everyone. You should speak to your doctor first if you: 

  • Intend to treat a child 

  • Have an allergy to hydrocortisone or local anaesthetics 

  • Are taking other medicines, like codeine, that could make you constipated 

  • Have a skin infection 

  • Are pregnant, trying to get pregnant, or are breastfeeding 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

What is the typical dosage of hydrocortisone?

The dosage depends on the form of the medicine you are using: 

  • Ointments and creams: Apply twice daily (morning and evening), and after bowel movements 

  • Suppositories: Insert one twice daily, and after bowel movements 

Do not use for more than 7 consecutive days without medical advice 

How do you take hydrocortisone?

Ointment[1]: 

  • Wash and gently dry the area 

  • Apply a small amount using clean fingers 

  • If using the applicator, insert gently into the rectum and squeeze while withdrawing 

Spray[1]: 

  • Push down on the pump once or twice before using it for the first time 

  • Wash hands before and after applying the spray  

  • Separate the buttocks and spray the area once 

Suppository[1]: 

  • Wash hands 

  • Remove the foil wrapper 

  • Insert the suppository, pointed end first, deep into the rectum and sit or lie still for 15 minutes 

  • Wash hands again 

Avoid using toilet paper to apply the ointment. Do not cover the treated area with dressings unless instructed.

Can you stop taking hydrocortisone?

If you’ve used it for less than 7 days, you can stop when symptoms improve. If you find that your symptoms aren’t improving and need to use it for longer, speak to your pharmacist or GP[1]. 

What do you do if you take too much hydrocortisone?

Occasionally using a little too much is not usually harmful. However[1]: 

  • Wipe off any excess ointment 

  • If you use too many suppositories or swallow one accidentally, contact your doctor 

  • Long-term overuse may cause hormonal side effects 

What do you do if you forget to take hydrocortisone?

If you miss a dose[1]: 

  • Apply or insert the medicine as soon as you remember 

  • If your next dose is due soon, skip the missed one 

  • Do not double the dose 

How do I store hydrocortisone?

Store the product correctly to ensure safety and effectiveness[1]: 

  • Keep below 25°C 

  • Store in original packaging 

  • Keep out of reach of children 

  • Do not use after the expiry date 

What medicines can’t you take with hydrocortisone?

This medicine is generally safe but may interact with certain other drugs. You should tell your doctor or pharmacist if you’re taking immunosuppressants like HIV medication or medicines that may cause or have caused you constipation[1]. 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of hydrocortisone?

Side effects are uncommon with short-term use, but some people may experience them. Common side effects include: 

  • Mild irritation or stinging 

  • Rash or itching around the anus 

  • Skin thinning around the anus after long-term use 

Rare or serious side effects include[1]: 

  • Inflamed skin around the bottom (sign of an infection 

  • Adrenal gland problems – upset stomach, vomiting, dizziness, fainting, muscle weakness, tiredness, mood changes, appetite loss, or weight loss 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1] 

  • Difficulty breathing  

  • Tightness in throat and chest  

  • Swelling of the tongue or throat  

  • Feeling faint or dizzy  

  • Blue/grey skin or lips  

  • Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about Hydrocortisone for Piles and Itchy Bottom

Can I use hydrocortisone during pregnancy? 
Only if prescribed by your doctor[1]. 

Can I use it while breastfeeding? 
Yes but speak with your doctor or pharmacist first[1]. 

Can I use hydrocortisone long-term? 
No – it should not be used beyond 7 days without medical advice[1]. 

Can children use it? 
Only under medical supervision[1]. 

Can I use hydrocortisone with other haemorrhoid products? 
Yes but check with your pharmacist[1]. 

Can I use it after haemorrhoid surgery? 
Yes, if advised by your doctor[1]. 

Does hydrocortisone cure piles? 
No – it relieves symptoms but doesn’t treat the underlying cause. Causative factors may include prolonged periods of constipation or diarrhoea. Speak to your pharmacist or doctor for advice[1]. 

Can I take painkillers with hydrocortisone? 
Yes, unless your doctor advises otherwise[1]. 

Can I drink alcohol with hydrocortisone? 
Yes – there’s no known interaction[1]. 

For the official NHS guide to hydrocortisone for piles and itchy bottom, visit their website. 


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The information provided on this Medicines A-Z page is intended for general informational purposes only and was accurate as of June 2025. It is designed to offer simple, patient-friendly summaries of prescribed medications based on publicly available resources, including those from the National Health Service (NHS). This content does not constitute medical advice, diagnosis, or treatment and is not a substitute for professional guidance from a qualified healthcare professional, such as a doctor or pharmacist.

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