Docusate

What is docusate?

Docusate, or docusate sodium, is a laxative used to prevent and relieve constipation. It may be prescribed or purchased over the counter sold under brands like DulcoEase, Dioctyl, Docusol, and Norgalax. It can also be used around certain medical procedures to prevent straining[1]. 

What is docusate used for?

Docusate is mainly used to relieve constipation by softening stools. This helps people with piles, who have difficult or dry poos, who have a tear in or near the anus, and those who should avoid straining during bowel movements, such as after surgery or childbirth. It can treat faecal impaction in some cases, under medical supervision[1]. 

How does docusate work?

Docusate is a stool softening medication. It works by increasing the amount of water absorbed by the stool in the gut, making the stool softer and easier to pass. It usually takes one to two days for docusate capsules or liquid to start working, whereas enemas can have an effect within 20 minutes[1]. 

Who can take docusate?

Docusate can be taken by most adults, and children over 12 years of age, with medical advice. Children under 12 may have docusate only if prescribed by a healthcare professional. It may be taken  by those pregnant or breastfeeding if advised by a doctor or pharmacist that it’s safe. 

However, docusate capsules or liquid may not be safe for people who[1]: 

• Are allergic to docusate or any of the ingredients listed as part of the medication  

• Have a blocked intestine 

• Are experiencing stomach pain, nausea or vomiting  

Docusate enemas should also not be used in people who[1]: 

• Have piles or bleeding from the bottom 

• Have a tear or sore around the anus 

• Have a paralytic ileus  

• Have ulcerative colitis, Crohn’s disease, or any other inflammatory bowel condition 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

How do you take docusate?

Docusate comes in capsules, liquid, or enemas. Take capsules with a full glass of water, with or without food. Take liquid dose as prescribed by your doctor followed by plenty of water, milk, or orange juice. If you are prescribed the liquid form, it is important to use the measuring spoon or oral syringe provided with the medication to ensure you are taking the correct dose. Kitchen teaspoons are not reliable and may lead to incorrect dosing.For the enema, squeeze the tube of liquid gently into your anus, following the instructions in the leaflet that comes with the medicine. It can work quickly, so be near a toilet between 5 and 20 minutes afterwards. For best results, take it at the same time daily[1]. 

What is the typical dosage of docusate?

For tablets and liquid, the typical dosage for adults and children aged 12 and over is 100mg, taken three times daily. For enema, the typical dosage is 120mg at a time. Doses for children will depend on age and weight - always follow a doctor or pharmacist’s advice[1]. 

Can you stop taking docusate suddenly?

You can usually stop taking docusate once your bowel movements have returned to normal. It is intended for short-term use only – unless a medical professional tells you otherwise[1]. 

What should you do if you take too much docusate?

Taking too much docusate may cause side effects such as diarrhoea, stomach cramps, and sometimes dehydration. If this happens, drink plenty of fluids and seek medical advice. You can call NHS 111 or contact your GP if you’re concerned[1]. 

What should you do if you forget a dose of docusate?

If you forget to take a dose of docusate, take it as soon as you remember. However, if it’s nearly time for your next dose, skip the missed one, and do not take a double dose to make up for it[1]. 

What medicines should you avoid while taking docusate?

You should check with your doctor or pharmacist before taking docusate with other laxatives, which may increase the risk of diarrhoea. You should also generally avoid taking it with mineral oil, as docusate can increase its absorption, which may be harmful[1].  

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of docusate?

Most people do not experience side effects when they have docusate. But in some cases, you might experience mild stomach cramps, diarrhoea, nausea, burning or pain around the bottom, mouth, or throat, and a skin rash (as a rare allergic reaction)[1].  

It’s important to get medical attention if you experience severe or persistent stomach pain or ongoing diarrhoea. 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about docusate

How long does docusate take to work? 

Docusate capsules and liquid usually work within one to two days after you’ve taken it[1]. 

Can I take docusate every day? 

Docusate is generally only prescribed for short-term use, unless advised by a doctor or pharmacist[1]. 

Is docusate safe during pregnancy? 

Yes, you can usually take docusate while pregnant, but only take it if your doctor has said it is safe to do so[1]. 

Can I take docusate with other laxatives? 

Docusate may be safe to take with some other laxatives, but only under medical supervision[1]. 

Can I drink alcohol while taking docusate? 

Alcohol does not interact with docusate, so it’s usually safe to drink  in moderation[1]. 

Is docusate addictive? 

No, docusate is not an addictive substance, but using any laxative too often can lead to dependence so use caution[1]. 

Can I take docusate long-term? 

You shouldn’t use docusate in the long term without your doctor or pharmacist’s advice and ongoing monitoring[1]. 

What is the difference between docusate and other laxatives? 

Docusate is a stool softener, while other laxatives may stimulate the bowel or draw water into it to soften the stool in different ways[1]. 

For the official NHS guide to docusate, visit their website.