Dexamethasone Tablets and Liquid

What are dexamethasone tablets and liquid?

Dexamethasone is a synthetic corticosteroid used to treat a wide range of inflammatory and immune-related conditions. Also known by brand names like Neofordex, Glensoludex, and Martapan, it’s a prescription-only medicine. It mimics natural hormones from the adrenal glands, helping to reduce inflammation, suppress immune responses, and regulate metabolism. Dexamethasone is available in two main forms[1]: 

• Tablets (typically 500 micrograms, 2mg, or 4mg) 

• Oral solution (e.g. 2mg/5ml) 

You can find advice here for dexamethasone eye drops.

What are dexamethasone tablets and liquid used for?

It may be prescribed for several different conditions, including[1]:

• Autoimmune diseases such as rheumatoid arthritis, lupus, and polymyalgia rheumatica 

• Inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis 

• Respiratory conditions including asthma and COPD 

• Neurological disorders such as cerebral oedema and multiple sclerosis 

• Severe skin disorders including eczema and Stevens-Johnson syndrome 

• Blood disorders such as leukaemia, myeloma, and idiopathic thrombocytopenic purpura 

• Croup 

• Cancer, as part of chemotherapy regimens 

• COVID-19 (for patients requiring oxygen therapy) 

• Organ transplant recipients to prevent rejection

How do dexamethasone tablets and liquid work?

Dexamethasone helps control inflammation and immune responses by[1]: 

• Suppressing immune system activity 

• Decreasing production of inflammatory chemicals 

• Reducing swelling and allergic reactions 

It also supports regulation of metabolism and fluid balance.

Who can take dexamethasone tablets and liquid?

Dexamethasone is widely used by adults and children, but it’s not appropriate for everyone. You should speak to the doctor first if you[1]: 

• Are allergic to dexamethasone 

• Have been in contact with someone who has shingles, chickenpox, or measles 

• Have an infection or untreated wounds 

• Have liver or kidney problems 

• Have ever had tuberculosis 

• Have high blood pressure, heart failure, or recently had a heart attack 

• Have diabetes, epilepsy, glaucoma, an underactive thyroid, osteoporosis, a stomach ulcer, or myasthenia gravis 

• Have had or are due to have vaccinations 

• Are pregnant, trying to get pregnant, or breastfeeding 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].

What is the typical dosage of dexamethasone tablets and liquid?

The correct dose depends on the patients age, the condition being treated,and individual response. It is important to take it as prescribed[1]. 

How do you take dexamethasone tablets and liquid?

To get the best results and minimise side effects:

• Take with or after food to reduce stomach irritation 

• Swallow tablets whole with water or for soluble tablets, dissolve them in water and drink it all 

• Measure liquid doses precisely using the spoon or syringe provided, not a kitchen teaspoon 

• Take at the same time each day, preferable after breakfast to help minimise stomach upset and sleep disturbance  

• Always follow your pharmacist or doctor’s instructions

Can you stop taking dexamethasone tablets and liquid?

No, you must not stop suddenly. Abrupt withdrawal can cause fatigue, low blood pressure, adrenal failure, or flare-up of your condition. Your doctor or pharmacist will advise on gradually reducing the dose[1]. 

What do you do if you take too much dexamethasone tablets and liquid?

An overdose can be serious. Seek medical help if necessary. Symptoms may include[1]:

• Muscle weakness 

• Mood changes 

• High blood sugar 

• Increased risk of infection 

What do you do if you forget to take dexamethasone tablets and liquid?

If you forget to take your medicine[1]:

• Take it as soon as you remember 

• If it's nearly time for your next dose, skip the missed one 

• Do not take a double dose 

How do I store dexamethasone tablets and liquid?

Store the medicine properly to maintain effectiveness[1]:

• Store below 25°C 

• Keep away from heat and moisture 

• Keep out of reach of children 

• Do not use after the expiry date 

What medicines can’t you take with dexamethasone tablets and liquid?

Dexamethasone can interact with several other medicines. Tell your pharmacist or doctor if you take[1]: 

• Blood thinners such as warfarin 

• NSAIDs including aspirin and indomethacin 

• Stomach medicines like antacids 

• Diuretics 

• Antibiotics such as rifampicin or erythromycin 

• Antifungals such as ketoconazole 

• HIV medications like ritonavir 

• Vaccines, particularly live ones 

• Antiepileptics like phenytoin and carbamazepine 

• Hormonal contraceptives 

• Cancer treatments such as thalidomide 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2].

What are the side effects of dexamethasone tablets and liquid?

While many people tolerate dexamethasone well, side effects can occur. The most common side effects include[1]: 

• Indigestion 

• Weight gain 

• Mood changes 

• Difficulty sleeping 

Serious side effects include[1]: 

• Mental health changes including depression or suicidal thoughts 

• High blood pressure 

• Diabetes 

• Osteoporosis 

• Eye changes or conditions such as glaucoma or cataracts 

• Greater risk of infections 

• Muscle weakness 

• Breathlessness 

• Heart palpitations 

• Hyperglycaemia 

• Red or black poo, or bleeding or bruising that is not normal 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2].

Frequently asked questions about dexamethasone tablets and liquid

Can I take dexamethasone long-term? 
Yes, but only under specialist supervision[1]. 

Can I drink alcohol with dexamethasone? 
Yes, in moderation[1]. 

Can I take it during pregnancy? 
Only if prescribed – your doctor will weigh risks and benefits[1]. 

Can children take dexamethasone? 
Yes, but their growth should be closely monitored[1]. 

Does dexamethasone affect fertility? 
There is no evidence that taking dexamethasone harms fertility in men or women[1]. 

Can I drive or operate machinery? 
Usually yes, unless you experience dizziness or visual issues[1]. 

Can I take dexamethasone with food? 
Yes – it helps reduce stomach irritation[1]. 

Do I need a steroid card? 
Yes, if you're taking it for more than 3 weeks and/or high doses[1]. 

Can I take dexamethasone with other steroids? 
Sometimes, but only under medical advice[1]. 

What if I get chickenpox or measles? 
Seek urgent medical advice – these infections can be severe while taking steroids[1]. 

For the official NHS guide to dexamethasone tablets and liquid, visit their website.

Medicines A-Z Directory Disclaimer

The information provided on this Medicines A-Z page is intended for general informational purposes only and was accurate as of June 2025. It is designed to offer simple, patient-friendly summaries of prescribed medications based on publicly available resources, including those from the National Health Service (NHS). This content does not constitute medical advice, diagnosis, or treatment and is not a substitute for professional guidance from a qualified healthcare professional, such as a doctor or pharmacist.

Patients should always consult their healthcare professional before starting, stopping, or changing any prescribed medication, and must inform them of any known allergies, medical conditions, or other medications being taken to ensure safe use. The inclusion of a medication on this page does not guarantee its availability, suitability, or approval for use in all cases, as prescribing decisions are made by healthcare professionals based on individual patient needs.

This page may include links to external websites, such as those maintained by the NHS or the Medicines and Healthcare products Regulatory Agency (MHRA), for further information. These links are provided for convenience only and do not imply endorsement. The pharmacy is not responsible for the content, accuracy, or availability of external websites, nor for any consequences arising from their use.

Medical and regulatory information may change over time due to new research, updated guidelines, or changes in licensing by the MHRA. While the pharmacy endeavours to keep this information accurate, it cannot guarantee its currency at all times. Patients are advised to verify information with a healthcare professional for the most up-to-date advice.

The pharmacy accepts no liability for any loss, damage, or injury resulting from the use of or reliance on the information provided on this page, including any consequences arising from self-diagnosis, self-medication, or failure to seek professional advice.