Candesartan

What is candesartan used for?

Candesartan is a medicine used to treat high blood pressure (hypertension) and heart failure, sometimes known by the brand name Amias. It belongs to a group of medicines known as angiotensin II receptor blockers (ARBs), which help relax and widen blood vessels. This makes it easier for your heart to pump blood and helps reduce the risk of complications like stroke or heart attack. Doctors may also prescribe candesartan to protect kidney function in people with diabetic kidney disease[1]. 

How does candesartan work?

Candesartan blocks the action of angiotensin II, a hormone that causes blood vessels to tighten. By blocking this hormone, candesartan helps to[1]: 

• Lower blood pressure 

• Reduce the workload on your heart 

• Improve blood flow 

• Prevent further damage to your heart and kidneys 

Who can take candesartan?

Candesartan is suitable for most adults and for children over 1 year old in certain cases. However, it may not be suitable for you if you[1]: 

• Are pregnant or breastfeeding 

• Have severe liver or kidney problems 

• Have very low blood pressure 

• Have high potassium levels in your blood 

• Are taking certain other medicines (e.g. ACE inhibitors or potassium supplements, aliskiren) 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].

What is the usual dose of candesartan?

Candesartan tablets come in strengths of 2mg, 4mg, 8mg, 16mg and 32mg. Your dose will depend on your condition and how well you respond to treatment[1]: 

• High blood pressure (adults): Starting dose is usually 8mg once a day, which may be increased to 16-32mg as needed 

• Heart failure (adults): Typically starts at 4mg once a day, gradually increased up to 32mg 

• Children over 6 years old: Dose is based on weight and must be determined by a specialist 

Always follow the instructions from your doctor or the information on your medicine label. 

How do you take candesartan?

Take once a day, at the same time each day if possible[1]: 

• Can be taken with or without food 

• Swallow tablets whole with a glass of water 

• Do not crush or chew unless advised by a healthcare professional

Can you stop taking candesartan?

Do not stop taking candesartan suddenly unless your doctor tells you to. Stopping could cause your blood pressure to rise again or worsen symptoms of heart failure. If you’re concerned about side effects or want to stop, speak to your GP[1].

What if you take too much candesartan?

Taking too much candesartan can cause[1]: 

• Dizziness or fainting 

• A very slow heart rate 

• Low blood pressure 

If you suspect an overdose, contact your GP, call NHS 111, or go to A&E immediately.

What if you forget a dose?

If you forget your dose[1]: 

• Take it as soon as you remember 

• If it's almost time for your next dose, skip the missed one 

• Do not take two doses at once to make up for a missed dose 

Medicines you can and can’t take with candesartan

Some medicines may affect how candesartan works or increase the risk of side effects. Speak to your doctor if you take[1]: 

• Other blood pressure medicines (e.g. ACE inhibitors) 

• Diuretics (water tablets) 

• NSAIDs such as ibuprofen – may reduce candesartan’s effectiveness 

• Potassium supplements or potassium-sparing diuretics – may increase potassium levels. It’s also a good idea to avoid salt subtitutes 

• Lithium – risk of lithium toxicity may be increased 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2].

What are the side effects of candesartan?

Most people tolerate candesartan well, but some may experience common side effects including[1]: 

• Dizziness or light-headedness (especially when standing up) 

• Headache 

• Cold or flu-like symptoms 

Serious (but rare) side effects include [1]: 

• Kidney problems 

• High potassium levels (can cause muscle weakness or irregular heartbeat) 

• Allergic reactions (rash, swelling, difficulty breathing) 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2].

Frequently asked questions about candesartan

Can I drink alcohol while taking candesartan? 
Yes, but alcohol may increase the risk of side effects like dizziness or fainting. Drink in moderation[1]. 

Will I need to take candesartan for life? 
Possibly – especially if you’re taking it to manage a long-term condition like hypertension or heart failure[1]. 

Can I take candesartan during pregnancy? 
No. It can cause harm to an unborn baby. Speak to your doctor about safer alternatives[1]. 

Can I drive while taking candesartan? 
Yes, unless you feel dizzy or tired. Avoid driving until you know how candesartan affects you[1]. 

How long does candesartan take to work? 
Blood pressure may start to lower within a few hours, but the full effect usually takes 2 to 4 weeks[1]. 

For the official NHS guide for candesartan, visit their website.