Betamethasone Tablets

What are betamethasone tablets?

Betamethasone is a corticosteroid used to reduce inflammation and suppress the immune system. It mimics the effects of hormones naturally produced by your adrenal glands. Betamethasone tablets are prescription-only and often come as soluble tablets that can be swallowed whole or dissolved in water[1]. 

Betamethasone also comes in other forms such as eye, ear and nose drops, eye ointment, and topical preparations to treat skin conditions. Read more here:

• betamethasone for eyes, ears and nose 

• betamethasone for skin 

What are betamethasone tablets used for?

These tablets are prescribed for a wide range of inflammatory or immune-related conditions, including[1]:

• Severe allergic reactions 

• Autoimmune diseases such as rheumatoid arthritis or lupus 

• Certain blood disorders 

• Inflammatory bowel disease (e.g. Crohn’s disease, ulcerative colitis) 

• Skin conditions such as eczema and psoriasis 

• Certain cancers including lymphoma and leukaemia 

• Congenital adrenal hyperplasia 

• To help prevent rejection after organ transplantation 

How do betamethasone tablets work?

Though not a painkiller, betamethasone works by calming the immune system and reducing inflammation. This can ease redness, swelling, and irritation, which often leads to less pain. This is especially true in conditions where the immune system is overactive such as severe allergies and autoimmune disorders[1]. 

Who can take betamethasone tablets?

It’s generally suitable for adults and children, but it may not be right for people who[1]:

• Have active infections, particularly viral ones like chickenpox or measles 

• Have unhealed wounds 

• Have recently had, or about to have, any vaccinations 

• Have conditions like: 

  ○ High blood pressure 

  ○ Eye infection 

  ○ Diabetes 

  ○ Any liver problem 

  ○ Osteoporosis 

  ○ Epilepsy 

  ○ Glaucoma 

  ○ Underactive thyroid (hypothyroidism) 

  ○ Stomach ulcers 

  ○ Heart failure or recently had a heart attack 

• Are pregnant or breastfeeding (speak to your doctor) 

• Have certain mental health conditions, as steroids can affect mood

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

Ask your doctor or pharmacist for a Steroid Treatment Card. This can be shown to healthcare professionals in an emergency or when you are prescribed new medicines. The card explains what steroid you are taking, the dose, and why you are taking it. This helps healthcare professionals give you the right treatment quickly and safely. 

What is the typical dosage of betamethasone tablets?

Betamethasone tablets contain 500mg of betamethasone. The dose will depend on your specific condition.  Your doctor may ask you to have regular reviews so that they can be sure the medicine is working[1]. 

How do you take betamethasone tablets?

Unless told otherwise by a doctor or pharmacist, take your tablets as a single dose straight after breakfast, to reduce the risk of side effects such as stomach upset and disturbed sleep. Swallow whole or dissolve in water if advised. If you are taking the dispersible preparation, make sure you finish all the water to get the complete dose. You can also split the tablets to make them easier to swallow[1]. 

Can you stop taking betamethasone tablets?

Do not stop taking betamethasone suddenly if you have been on a high dose or if you have been taking it for a few weeks. In this case, your doctor will reduce your dose gradually. This helps prevent withdrawal symptoms and lowers the risk of adrenal gland problems. 

Signs of adrenal problems include extreme tiredness, dizziness, feeling or being sick, loss of appetite, stomach pain, and weight loss. If you notice these symptoms, contact your doctor eight away. Call 999 if you feel very unwell for example collapse or cannot stay awake[1]. 

What do you do if you take too many betamethasone tablets?

Taking too much can cause serious side effects such as high blood pressure, fluid retention, or hormonal imbalances. Seek emergency medical help immediately[1]. 

What do you do if you forget to take betamethasone tablets?

If you forget to take a dose, take it as soon as you remember unless it’s close to your next dose. Never take two doses at the same time[1].

How do you store betamethasone tablets?

Store in a cool, dry place away from direct sunlight. Keep out of reach of children. Don’t use it after the expiry date[1]. 

What medicines can’t you take with betamethasone tablets?

Betamethasone can interact with several medicines, including[1][3]: 

• NSAIDs such as ibuprofen (can increase risk of stomach bleed) 

• Diuretics (can affect potassium levels) 

• Vaccinations (their effectiveness may be reduced. Live vaccines should also be avoided if your corticosteroids are given for immunosuppression) 

• Some antifungals and antibiotics 

• Liquorice or liquorice-based products (can increase side effects) 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of betamethasone tablets?

Common side effects of betamethasone include[1]: 

• Weight gain 

• Indigestion 

• Trouble sleeping 

• Mood changes and restlessness 

• Sweating 

• Increased susceptibility to infections 

The chances of experiencing serious side effects increase with higher doses and longer treatment times. These include[1]: 

• Eye conditions like glaucoma or cataracts 

• High blood pressure or diabetes 

• Muscle weakness 

• Thinning bones (osteoporosis) 

• A high temperature, sore throat, ear or sinus pain, coughing, pain peeing, mouth sores, or a wound that won’t heal – a sign of infection 

• High blood sugar – confusion, increased thirst or hunger, and peeing frequently 

• Cushing’s syndrome – weight gain in upper back or stomach, puffy, rounded face, and slow wound healing 

• Adrenal gland problems – sickness, dizziness, passing out, muscle weakness, extreme tiredness, loss of weight, and loss of appetite 

• Low potassium levels 

• Pancreas problems 

• Swollen limbs 

• Blurred vision 

• Unexplained bruising or bleeding 

• Breathing problems with black poo, or dark vomit – call 999 or go to A&E immediately 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about betamethasone tablets

How long do betamethasone tablets take to work? 
Relief usually begins within a few days[1]. 

Can I drink alcohol while taking betamethasone tablets? 
Yes, in moderation[1]. 

Will it cause weight gain? 
It can, particularly with long-term use[1]. 

Can I drive on betamethasone tablets? 
Yes, unless you feel dizzy or drowsy[1]. 

Are betamethasone tablets addictive? 
No, but don’t stop suddenly if you’ve been taking it for a long time[1]. 

Can I take betamethasone tablets long-term? 
Yes, under close medical supervision[1]. 

Can I take betamethasone tablets during pregnancy? 
Only if recommended by your doctor[1]. 

What if I develop an infection? 
Contact your GP immediately – you may need to stop or change your treatment[1]. 

Do I need a steroid card? 
Yes, if you’re taking it for more than 3 weeks or at a high dose. Speak to your doctor if this is the case[1]. 

For the official NHS guide to betamethasone tablets, visit their website.