Betahistine

What is betahistine?

Betahistine is a prescription-only medicine primarily used to treat Ménière’s disease, a condition affecting the inner ear that causes vertigo (dizziness and spinning sensation), tinnitus (ringing in the ears), nausea, and hearing loss. It’s often sold under the brand name Serc[1].

What is betahistine used to treat? 

Betahistine is used to relieve symptoms of[1]: 

• Relieving symptoms of vertigo 

• Reducing tinnitus 

• Improving hearing loss 

These symptoms are usually linked to Ménière’s disease and other balance disorders[1]. 

How does betahistine work?

Betahistine works by[1]: 

• Improving blood flow in the inner ear to reduce pressure build-up 

• Blocking histamine H3-receptor leading to an increase in neurotransmitters, easing vertigo and tinnitus 

Who can take betahistine?

Betahistine is suitable for most adults but not recommended for children. You should inform your doctor if you[1]: 

• Have asthma 

• Have stomach ulcers or history of ulcers 

• Have low blood pressure 

• Are pregnant or breastfeeding 

• Have pheochromocytoma 

• Are allergic to betahistine or to any of the other ingredients of this medicine 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

What is the typical dosage of betahistine?

Betahistine comes as 8mg or 16mg tablets. The usual starting dose is 16mg, taken 3 times a day, but this depends on your doctor’s instructions. When your symptoms are under control, your doctor may reduce your dose to 8mg, taken 3 times a day[1]. 

How do you take betahistine?

Take it with or after food to help reduce stomach upset. Swallow tablets whole with water. It’s best to take betahistine at the same time each day for steady effect and leave between 6 to 8 hours between doses[1]. 

Can you stop taking betahistine?

Yes, but don’t stop suddenly without consulting your doctor as stopping too early may cause symptoms to return[1]. 

What do you do if you take too much betahistine?

If you take more than your prescribed dose: 

• Symptoms may include nausea, sleepiness, or stomach pain 

• Contact your GP or call 111 for advice 

• In an emergency, go to A&E with your medicine packaging 

What do you do if you forget a dose of betahistine?

If you miss your dose, take it as soon as you remember. Skip if close to next dose and don’t double dose[1]. 

Medicines you can and can’t take with betahistine

Avoid taking betahistine with[1]: 

• Antihistamines (e.g., cetirizine, loratadine) – may reduce effectiveness 

• Monoamine oxidase inhibitors (MAOIs) – may increase side effects 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

Side effects of betahistine

Most people tolerate betahistine well, however, the most common side effects include[1]: 

• Headache 

• Nausea 

• Indigestion or bloating or other gastrointestinal discomfort 

Rare but serious side effects include[1]: 

• Allergic reactions (rash, itching, swelling) 

• Severe stomach pain 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include:

• Difficulty breathing

• Tightness in throat and chest

• Swelling of the tongue or throat

• Feeling faint or dizzy

• Blue/grey skin or lips

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about betahistine

How long does betahistine take to work? 
It may take a few weeks before you notice improvement[1]. 

Can I drink alcohol while taking betahistine? 
Yes, but alcohol may worsen vertigo symptoms[1]. 

Is betahistine safe during pregnancy? 
Only take if prescribed by your doctor during pregnancy or when breastfeeding. It’s not usually recommended during pregnancy or breastfeeding[1]. 

Can I drive or operate machinery while taking beastie? 
Betahistine itself doesn’t cause dizziness, but your condition might. Avoid driving if you feel dizzy or sick[1]. 

For the official NHS guide for betahistine, visit their website.