Fusidic Acid

What is fusidic acid?

Fusidic acid is an antibiotic used to treat bacterial infections, particularly those affecting the skin and eyes. Sometimes known as sodium fusidate, it is available in several forms, including creams, ointments, eye drops, and tablets. Brand names include Fucidin, Fucithalmic, and Fucidin H (which combines fusidic acid with hydrocortisone)[1]. 

What is fusidic acid used for?

Doctors commonly prescribe fusidic acid for the following conditions[1]: 

• Impetigo, a contagious skin infection 

• Infected eczema or dermatitis 

• Infected cuts, grazes, or wounds 

• Eye infections such as conjunctivitis (when in eye drop form) 

• Other susceptible infections 

How does fusidic acid work?

Fusidic acid works by inhibiting bacterial protein synthesis, which stops bacteria from growing and multiplying. It is particularly effective against Staphylococcus aureus, including some strains of MRSA[1]. 

Always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

Who can take fusidic acid?

Fusidic acid is generally considered safe for the following groups[1]: 

• Adults and children 

• Pregnant and breastfeeding women, when used under medical supervision 

• People with mild to moderate skin infections 

However, it should not be used by anyone with a known allergy to fusidic acid or any of the ingredients listed as part of your medicine. 

Please tell your doctor or pharmacist about any conditions you may have or medication you take before you start treatment, and always follow the instructions in the Patient Information Leaflet[2].  

How do you take fusidic acid?

Follow these instructions depending on the form you're using[1]: 

• For topical creams or ointments, apply a thin layer to the affected area, wash your hands before and after 

• For eye drops, tilt your head back, pull down the lower eyelid, and apply one drop as directed 

• For tablets, swallow them whole with water, with or without food 

What is the typical dosage of fusidic acid?

The dosage and form depend on the condition being treated[1]: 

• Cream or ointment is usually applied 3 to 4 times a day 

• Eye drops are typically used twice daily (one drop per affected eye) 

• Tablets should be taken exactly as prescribed by your doctor 

Can you stop taking fusidic acid?

No, you should complete the full prescribed course, even if your symptoms improve. Stopping treatment too soon can allow the infection to return or become resistant[1]. 

What do you do if you take too much fusidic acid?

Here’s what to do in the event of an overdose[1]: 

• If you apply too much topically, wipe off the excess. This is unlikely to cause harm. 

• If you take too many tablets, contact a doctor, pharmacist or go to A&E immediately.  

What do you do if you forget to take fusidic acid?

If you forget to use or take a dose[1]: 

• Use or take it as soon as you remember. 

• If it’s nearly time for your next dose, skip the missed one. Never take or apply a double dose to make up for it. 

What medicines can’t you take with fusidic acid?

Interactions between eye drop and topical fusidic acid preparations and any medicines, herbal remedies, or supplements are unlikely due to little absorption into the body[1]. Oral sodium fusidate tablets will be absorbed by the body and may interact with the following: 

• Statins 

• HIV medication 

• Anticoagulants such as warfarin 

However, you should always inform your doctor or pharmacist about all medications and supplements you take before you start a new medicine, and follow the instructions in the Patient Information Leaflet[2]. 

What are the side effects of fusidic acid?

Like all medicines, fusidic acid can cause side effects even if it is uncommon in this case. The most prevalent ones include[1]: 

• Skin irritation, itching, or rash 

• Stinging or burning when using eye drops 

• Contact dermatitis 

• Blurred vision 

For the cream, ointment, or eye drops, serious side effects occur in less than 1 in 1,000 people and can include conjunctivitis and hives[1]. 

You should contact your GP if you experience any of these symptoms. In rare cases, the medicine may cause a serious allergic reaction (anaphylaxis). You should call 999 or visit A&E immediately if you believe this is happening[1]. 

Symptoms of anaphylaxis include[1]:  

• Difficulty breathing  

• Tightness in throat and chest  

• Swelling of the tongue or throat  

• Feeling faint or dizzy  

• Blue/grey skin or lips  

• Loss of consciousness 

If you experience any side effects, including those not listed, you are encouraged to report them via the Yellow Card Scheme or contact your doctor, pharmacist, or nurse. This information is intended as a summary for general awareness and does not replace professional medical advice. 

The information provided in the side effects section is not a comprehensive list of all possible side effects associated with this medication. For a complete list of side effects, please refer to the Patient Information Leaflet (PIL) provided with your medication or consult your healthcare professional[2]. 

Frequently asked questions about perindopril

Can I use topical fusidic acid on open wounds? 
Yes, you can use it on open wounds such as infected cuts or grazes, but only if it has been prescribed for that purpose[1]. 

Is fusidic acid safe during pregnancy? 
Topical fusidic acid is generally considered safe during pregnancy, but you should consult your doctor before using it[1]. 

Can I drive or ride a bike while taking fusidic acid? 
You may get blurred vision for a short time after putting in eye drops. Wait for your vision to clear[1].  

Can I drink alcohol while using fusidic acid? 
Yes, there are no known interactions between fusidic acid and alcohol, so drinking in moderation is generally safe[1]. 

For the official NHS guide to fusidic acid, visit their website.