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Complete a discreet online consultation with our doctors and find out if tadalafil could be the solution to your erecticle dysfunction.

  • Improves the ability to obtain and maintain an erection
  • Allows increased blood flow to the penis
  • Effective for up to 36 hours after taking.

*Please note images are for illustration purposes and the packaging you receive may differ

Strength i

  • 2.5mg Daily
  • 5mg Daily
  • 10mg 36 hour
  • 20mg 36 hour

Generic or branded i

  • Tadalafil (Generic Tadalafil)

£50.00 (£1.79 per tablet)

In Stock

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Our Doctor says...

Tadalafil is the generic version of Cialis. This means that it contains the same ingredient as Cialis but is made by a different manufacturer. It is used in the same way as Cialis and has the same benefits as the branded version.

Dr. Alex Phelan Pharmacy2U Online Doctor

More information about Tadalafil

How to take Tadalafil

Tadalafil can be taken in two ways. For more spontaneity, it can be taken regularly, once daily as a 2.5mg or 5mg dose, to keep it in your system; this means you can enjoy sex without planning ahead or thinking about taking a tablet at a particular time. It takes about five days at first to become fully effective. Alternatively, it can be taken at a higher 10mg or 20mg dose just when it's required. When taking it like that, you should take a 10mg or 20mg tadalafil tablet at least 30 to 60 minutes before you have sex. Either way, it can take a few attempts for any erectile dysfunction medication to work, and sexual arousal is still required for it to have any effect.


When taken on an 'as required' basis, the usual starting dose is a 10mg tablet, around 30 to 60 minutes before sex, up to once in a 24 hour period. If this does not work for you after at least 4 attempts, and no side effects are experienced, the dosage can be increased to a 20mg tablet. If taken on a daily basis, a 5mg tablet should be taken every day at the same time. If desired, or if side effects are experienced, this can be reduced to a 2.5mg tablet. No more than 20mg should be taken in a 24 hour period.


Tadalafil is an effective treatment for erectile dysfunction. Once taken, tadalafil can work for up to 36 hours, meaning it can be taken ahead of being needed, reducing some of the need for pre-planning before sex. Food does not affect the speed at which the drug works.

Side Effects

As with all medicines, tadalafil can cause side effects, but not everyone experiences them. If taken at the recommended dosage, the side effects of this drug are usually mild and will pass with time. The most common side effects are headaches or an upset stomach. You may experience flushing, dizziness, memory problems, muscle pain or flu-like symptoms. More serious side effects include low blood pressure, blurred vision or abnormal ejaculation. If you experience any of these, or a prolonged and painful erection, stop using the medicine and seek medical assistance immediately.

Nitrates and Alpha Blockers

Taking tadalafil with medicines known as nitrates can cause a drastic drop in blood pressure. Nitrates are usually found in drugs used to treat chest pain and angina, and in the recreational drug ?poppers?. It is also not recommended to combine medicines called 'alpha blockers' with tadalafil. Always check with your doctor before combining any medicines and make sure you tell our doctors about any other medications you take. Always read the leaflet carefully before taking any medicine.

How long does it take to work?

Tadalafil should be taken at least thirty minutes before required. It can be safely taken several hours before it's needed as it stays in the body for up to 36 hours. Tadalafil may not work for everyone the first time it's taken; give yourself four to eight attempts with the drug before trying a different option.

How long does it last?

Tadalafil stays in your system for up to 36 hours. Most of the other medication options for erectile dysfunction only last four to five hours, so the extended time of tadalafil allows you to have more spontaneous sex, with less advance planning required.

How does it work?

An erection occurs when the penis fills with blood. The blood vessels that bring blood to the penis dilate, increasing the blood supply. Blood accumulates in the penis, causing an erection. Tadalafil works by increasing the blood flow into the penis, enabling a man to achieve an erection. It does not increase sexual arousal.

Who should take tadalafil?

Tadalafil is a generic medication for erectile dysfunction. If you have trouble getting or maintaining an erection, ask our online doctors about tadalafil. Remember, this drug can only be supplied with a prescription.

Who should not take tadalafil?

Do not take this drug if you have an allergy to tadalafil or any of the other listed ingredients. Tadalafil is not suitable for those with serious heart disease, those who have experienced a recent heart attack or stroke, or those with hypotension (low blood pressure). This is because the medication itself or increased sexual activity could put an extra strain on your heart. You must tell our doctors if you have had any past issues with your vision, or if you have or have ever had sickle cell anaemia, multiple myeloma, leukaemia, a penis deformity or liver or kidney problems. Tadalafil is not suitable for use by women, or those under 18 years of age.

How do I take tadalafil?

Tadalafil comes as an easy to swallow tablet, which should be taken orally, with a glass of water. You can take the tablet with or without food. Alcohol may have a negative impact on the effect of the drug.

Can I take Tadalafil with other medication?

Patients taking any nitrate medication or Riociguat should not take tadalafil. These medications could interact and cause unexpected side effects. You must let your doctor know if you are taking any other medications, whether prescribed or purchased over the counter, especially alpha blockers, any high blood pressure medication, 5-alpha reductase inhibitors, protease inhibitors, phenobarbital, phenytoin, carbamazepine, rifampicin, erythromycin, clarithromycin or itraconazole. It is also important to let us know if you use, or have used, other erectile dysfunction medications.

"If tadalafil does not work for you, there are other medications available. You could try Viagra (sildenafil), Levitra (vardenafil) or Spedra (avanafil). Tadalafil and Cialis, in 2.5mg and 5mg strengths, are the only ones that can be taken on a regular daily basis, whereas the other medicines are only intended for use as and when required. Viagra is effective for most men with erection problems. Viagra comes in a blue pill in strengths of 25mg, 50mg and 100mg. Levitra comes in strengths of 5mg, 10mg and 20mg. It has been shown to be effective in a wide range of age groups and for men with conditions such as high blood pressure, diabetes, depression and high cholesterol. Spedra comes in strengths of 50mg, 100mg and 200mg, and has been shown to work well for men with erectile dysfunction caused by type 1 and type 2 diabetes. Spedra can work within 15-30 minutes of taking the dose - this is a faster onset of action than Viagra, Levitra or Cialis."


Can I take tadalafil and drink alcohol?

Most erectile dysfunction medicines can lower your blood pressure, as does alcohol. Combining the two could cause you to experience light-headedness, dizziness, fainting or heart palpitations. Alcohol could also have an impact on the effectiveness of the medicine.

Can young men get ED?

Older men are more likely to experience erectile dysfunction, but younger men can be affected too. Causes can be physical or psychological.

Is tadalafil safe?

Tadalafil has been rigorously tested in order to confirm its safety. The doctor or pharmacist who assesses your condition will check for any potentially dangerous contra-indications, such as certain health problems or interactions with other medicines you take.

How will my medication be delivered?

Your medication will arrive in discreet packacing, via Royal Mail. We can deliver to any UK address, so you can choose home, work or any other address. Where possible, our deliveries will fit through your letterbox. Some fridge items and controlled drugs must be sent tracked signature.