What is Livial?
Livial tablets contain the active ingredient tibolone in a strength of 2.5mg per tablet.
Livial is a medicine that has similar properties in the body to both oestrogen and progestogen hormones, and some properties of androgen hormones too. This means that it can be used to relieve symptoms of the menopause, and it is sometimes prescribed to prevent osteoporosis in women after the menopause.
Livial should not cause a monthly bleed, but you may experience some bleeding or spotting in the first four to six months of use as your body adapts to it. It should only be used if your last natural bleed was over a year ago.
How to take Livial Tablets
You should always read the enclosed leaflet carefully before taking Livial.
The dose is one tablet to be taken each day, at around the same time. You can take it before or after food. The tablets are taken continuously without a break between packs.
Are Livial suitable for me?
There are some situations in which Livial, like all medicines, should be used with caution or is likely to not be recommended at all. This may be true, for example, in women over 65, or women with cancer or a history of cancer; undiagnosed genital bleeding; liver or kidney problems or untreated endometrial hyperplasia (excessive growth of tissue in the womb); women who currently have, or have previously had, venous thromboembolism (deep vein thrombosis, or pulmonary embolism); disorders of blood clotting; circulation problems including heart disease, angina, or a heart attack or porphyria; people who are allergic to any of the active or inactive ingredients.
In addition, it is important to mention to the online doctor if you currently have, or have had in the past, any of these conditions: endometriosis, risk factors for thromboembolic disorders (for example major surgery, prolonged immobilisation, obesity, cancer, smoking or excessive drinking) or risk factors for oestrogen dependent tumours (for example first-degree heredity for breast cancer). You should also mention to the doctor if you’ve ever had hypertension, liver or kidney problems (including liver adenoma), diabetes mellitus with or without vascular involvement, cholelithiasis, migraine or (severe) headache, systemic lupus erythematosus (SLE), a history of endometrial hyperplasia, epilepsy, asthma, or otosclerosis.
During your consultation, please be sure to tell the doctor if you are taking any other medicines, either from your doctor or from a pharmacy without a prescription. Livial can cause problems if used at the same time as certain other medicines, including some medicines for epilepsy and infections (for example rifampicin). Let us know if you’re taking warfarin or other anticoagulants, midazolam, and St John's Wort (a herbal preparation).
You should always be honest about your general health in the consultation. This is to make sure the doctor has all the information needed when assessing whether Livial is suitable for you.
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What are the side effects of Livial?
You should be aware that, like all medicines, if you take Livial, there is the potential you may experience side effects.
Some of these side effects are potentially serious. If you experience any of the following, you should stop using Livial and tell your local doctor immediately:
- Unexplained vaginal bleeding, especially bleeding or spotting that carries on for more than the first six months, starts after you’ve been taking Livial for more than six months, or carries on even after you have stopped taking Livial
- Painful menstrual periods
- Painful swelling and redness of the legs
- Sudden chest pain
- Difficulty in breathing
- Pain in your chest that spreads to your arm or neck
- Yellowing of the eyes and face (jaundice)
- Rapid increase in your blood pressure
- Unexplained migraine-like headaches
- Breast changes, including dimpling of the breast skin, changes in the nipple and lumps that you can see or feel.
Other side effects that have been reported include abdominal pain, abnormal hair growth, vaginal itching or discharge, breast tenderness, vaginal thrush, pelvic pain, weight changes, and acne.
Hormone replacement therapy (HRT) increases the risk of thrombosis (blood clots), stroke, breast cancer, and ovarian cancer. Therefore, the minimum effective dose of HRT should be used, for the shortest length of time.
You can find a full list of potential side effects and any other important information, on the patient information leaflet provided in the pack. The leaflet can also be viewed online here, and you should read this before starting any treatment.
Online consultations are available through the Pharmacy2U Online Doctor service, which could lead to a prescription of Livial tablets.